Antioxidant Activity of Chemical Constituents Isolated from Pithecellobium clypearia
نویسندگان
چکیده
Phytochemical investigation of the aqueous extract of Pithecellobium clypearia afforded one novel compound, clypearoside A (1), and one new stereoisomer, (-)-(2S,3S)-epigallocatechin-7-gallate (2) and four known ones (3-6). Their structures were elucidated on the basis of spectroscopic data, especially 2D NMR, HRESIMS and ECD spectra. Compounds 2-4 showed strong activity against DPPH (diphenylpicrylhydrazyl) and ABTS (2,2’-azino-bis(3-ethylbenzothiazoline-6-sulphonate) with an IC50 value of 11.9-13.2 μg/mL (DPPH) and 4.5-6.4 μg/mL (ABTS).
منابع مشابه
Studies on the bioactive flavonoids isolated from Pithecellobium clypearia Benth.
One new flavonoid named (2R,3R)-7-O-galloylplumbocatechin A (1) and three known flavonoids, (-)-5,3',4',5'-tetrahydroxyflavan-7-gallate (2), (+)-3,5,3',4',5'-penta-hydroxyflavan-7-gallate (3), and (-)-7,4'-di-O-galloyltricetiflavan (4), were isolated from Pithecellobium clypearia Benth. Their structures were elucidated based on spectroscopic analysis, including homonuclear and heteronuclear cor...
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